Dr. Alexander Schacht

All Episodes

What can we do about indirect comparisons to make it better and more efficient rather than using the usual technique?
What are the indirect comparisons in terms of the efficacy of different drugs?
What experiences have you had when the type of one-to-one approach is better?

In today’s episode, Daniel and I talk about these questions and discuss more the following points:

• Bucher vs MAIC – advantages and disadvantages
• Methodik MAIC
• NICE technical document (http://nicedsu.org.uk/technical-support-documents/population-adjusted-indirect-comparisons-maic-and-stc/) – including R code

Weiterlesen …

Everything you need to know about matching adjusted indirect comparisons

Dr. Alexander Schacht

All Episodes

What can we do about indirect comparisons to make it better and more efficient rather than using the usual technique?
What are the indirect comparisons in terms of the efficacy of different drugs?
What experiences have you had when the type of one-to-one approach is better?

In today’s episode, Daniel and I talk about these questions and discuss more the following points:

• Bucher vs MAIC – advantages and disadvantages
• Methodik MAIC
• NICE technical document (http://nicedsu.org.uk/technical-support-documents/population-adjusted-indirect-comparisons-maic-and-stc/) – including R code

Weiterlesen …

Dr. Alexander Schacht

All Episodes

Given the pandemic, this episode comes timely as it’s a challenge to manage time while working at home.

But even after the pandemic, this challenge of getting most out of your time will not end.

In today’s episode, Benjamin and I talk about different time management hacks to be productive and efficient while working at home.

We talk specifically about these points:

Things you should establish first:

• Be clear on your goals and keep them in front of you
• Focus on building great habits as these will carry you to success

Three time management hacks:

1. Saying no and turning things back – reflect work
2. Focus your efforts and concentration (schedule time, manage distractions)
3. Get and stay organized (calendar, to-dos, meetings, filing ….) – apply the 4 principles from Atomic Habits

Weiterlesen …

3 Time Management Hacks, That Actually Work

Dr. Alexander Schacht

All Episodes

Given the pandemic, this episode comes timely as it’s a challenge to manage time while working at home.

But even after the pandemic, this challenge of getting most out of your time will not end.

In today’s episode, Benjamin and I talk about different time management hacks to be productive and efficient while working at home.

We talk specifically about these points:

Things you should establish first:

• Be clear on your goals and keep them in front of you
• Focus on building great habits as these will carry you to success

Three time management hacks:

1. Saying no and turning things back – reflect work
2. Focus your efforts and concentration (schedule time, manage distractions)
3. Get and stay organized (calendar, to-dos, meetings, filing ….) – apply the 4 principles from Atomic Habits

Weiterlesen …

Dr. Alexander Schacht

All Episodes

Imagine you need to choose a comparator for a head-to-head study. How do we usually approach it?

• Debate
• Meetings
• More meetings with other stakeholders
• Creating a slide deck
• Revising the slide deck
• Getting into time pressure
• Getting conflicting feedback
• Let’s just make a recommendation and find the data that supports this

In today’s episode, we discuss how to manage problems with efficiency, clarity, logic, consistency, alignment, and speed.

Weiterlesen …

8 Steps to make a Smart Decision

Dr. Alexander Schacht

All Episodes

Imagine you need to choose a comparator for a head-to-head study. How do we usually approach it?

• Debate
• Meetings
• More meetings with other stakeholders
• Creating a slide deck
• Revising the slide deck
• Getting into time pressure
• Getting conflicting feedback
• Let’s just make a recommendation and find the data that supports this

In today’s episode, we discuss how to manage problems with efficiency, clarity, logic, consistency, alignment, and speed.

Weiterlesen …

Dr. Alexander Schacht

All Episodes

Have you been sitting through boring presentations?
Have you felt that the presenter lost the audience in seconds?
Have you found yourself after a presentation thinking – so what?

When you are presenting, you don’t want the audience to feel this way. But how can you deliver a knock-out presentation and wow the audience?

In today’s episode, Benjamin and I discuss 14 presentation tips that really work. We speak about:

1. Be clear on your goals
2. Have a strong start
   • Start with a story, conclusions, then introduce yourself 
   • Enter the room or stage with confidence 
3. Speak to Ethos, Pathos and Logos
4. Establish a powerful position 
5. Make eye contact 
6. Smile 
7. Never lean back when sitting – better stand up
8. Dress appropriately
   • Avoid anything distracting 
   • Appear confidently
9. Position your camera well
10. Use pauses intentionally 

Weiterlesen …

Present like a Pro – 14 Presentation Tips

Dr. Alexander Schacht

All Episodes

Have you been sitting through boring presentations?
Have you felt that the presenter lost the audience in seconds?
Have you found yourself after a presentation thinking – so what?

When you are presenting, you don’t want the audience to feel this way. But how can you deliver a knock-out presentation and wow the audience?

In today’s episode, Benjamin and I discuss 14 presentation tips that really work. We speak about:

1. Be clear on your goals
2. Have a strong start
   • Start with a story, conclusions, then introduce yourself 
   • Enter the room or stage with confidence 
3. Speak to Ethos, Pathos and Logos
4. Establish a powerful position 
5. Make eye contact 
6. Smile 
7. Never lean back when sitting – better stand up
8. Dress appropriately
   • Avoid anything distracting 
   • Appear confidently
9. Position your camera well
10. Use pauses intentionally 

Weiterlesen …

Dr. Alexander Schacht

All Episodes

As statisticians, we often need to bring terrible news to the team. We’re the first to know, that a study didn’t reach the primary endpoint, or that safety analyses showed some new signals, or that some analyses contained mistakes, that need to be corrected.

How do you deal with such situations?

In today’s episode, Benjamin and I discuss the following points:

• First mover advantage
• Preparing and planning
  • Be clear on your goals
  • Who do you want to move from A to B 
  • What questions will come up?
  • What will be our replies?
  • What will be the follow-up questions?
  • Who will be affected?
  • Who needs/must know first?
  • How do you communicate it?

Weiterlesen …

Failed Study, New Safety Finding, Mistakes – Breaking Bad News

Dr. Alexander Schacht

All Episodes

As statisticians, we often need to bring terrible news to the team. We’re the first to know, that a study didn’t reach the primary endpoint, or that safety analyses showed some new signals, or that some analyses contained mistakes, that need to be corrected.

How do you deal with such situations?

In today’s episode, Benjamin and I discuss the following points:

• First mover advantage
• Preparing and planning
  • Be clear on your goals
  • Who do you want to move from A to B 
  • What questions will come up?
  • What will be our replies?
  • What will be the follow-up questions?
  • Who will be affected?
  • Who needs/must know first?
  • How do you communicate it?

Weiterlesen …