Dr. Alexander Schacht

All Episodes

Frank has something in common with Benjamin and myself – we all studied statistics in Göttingen and learned and researched in non-parametric statistics. Afterwards, we went into different paths. Whereas Benjamin started at a CRO and I joined large pharma organizations, Frank continued on the academic track.

He recently became Professor at the famous Charitee in Berlin, where he’s still dedicating a lot of research to the field of non-parametric statistics. However, he’s not an ivory tower researcher but also applies these approaches in the medical research he’s taking part in. 

Learn about a whole universe of different approaches, which will help you overcome many limitations of the methods, which you’re using daily.

Weiterlesen …

Non-parametric analyses – much more than just the Wilcoxon test!

Dr. Alexander Schacht

All Episodes

Frank has something in common with Benjamin and myself – we all studied statistics in Göttingen and learned and researched in non-parametric statistics. Afterwards, we went into different paths. Whereas Benjamin started at a CRO and I joined large pharma organizations, Frank continued on the academic track.

He recently became Professor at the famous Charitee in Berlin, where he’s still dedicating a lot of research to the field of non-parametric statistics. However, he’s not an ivory tower researcher but also applies these approaches in the medical research he’s taking part in. 

Learn about a whole universe of different approaches, which will help you overcome many limitations of the methods, which you’re using daily.

Weiterlesen …

Dr. Alexander Schacht

All Episodes

Why do you think many of these “subgroup” projects are a headache for statisticians?
Have you felt frustrated about such projects yourself?
What are the steps to avoid or at least minimize these frustrations?

Do you have the same questions in mind? These are some of the questions Necdet will be answering and sharing with us.

This episode is based on a presentation at PSI 2019. Necdet won The Effective Statistician Best Presenter award for the amazing delivery of the presentation. But not only the delivery was excellent – the content will help you a lot. Here’s the abstract for the conference.

Abstract: Practical aspects of subgroup detection

Recent years have seen the emergence of new methods for detecting subgroups with enhanced treatment effects and statisticians are now faced with an overwhelming choice of approaches to consider. Confusion around the potential advantages and disadvantages of different methods can often result in the implementation of an approach that is not appropriate for a particular research question.

Weiterlesen …

Taking the pain out of subgroup analyses

Dr. Alexander Schacht

All Episodes

Why do you think many of these “subgroup” projects are a headache for statisticians?
Have you felt frustrated about such projects yourself?
What are the steps to avoid or at least minimize these frustrations?

Do you have the same questions in mind? These are some of the questions Necdet will be answering and sharing with us.

This episode is based on a presentation at PSI 2019. Necdet won The Effective Statistician Best Presenter award for the amazing delivery of the presentation. But not only the delivery was excellent – the content will help you a lot. Here’s the abstract for the conference.

Abstract: Practical aspects of subgroup detection

Recent years have seen the emergence of new methods for detecting subgroups with enhanced treatment effects and statisticians are now faced with an overwhelming choice of approaches to consider. Confusion around the potential advantages and disadvantages of different methods can often result in the implementation of an approach that is not appropriate for a particular research question.

Weiterlesen …

Dr. Alexander Schacht

All Episodes

A replay of the PSI Conference 2018

Are you a sponsor who is seeking joint scientific advice from a regulatory agency and an HTA body?

If yes, this episode is for you. This presentation replicates the discussions which may go on during scientific advice. The example was in Respiratory. This roleplay was played by David Wright, Oliver Keene, Stephen Ruberg, and myself. Mouna Akacha moderated the discussion. The aim was to show a couple of discussion points and an interesting aspect that may come up with such discussions.

A lively debate followed about the differing needs of Regulatory agencies vs HTA, with the patient voice often not taking center stage.

Weiterlesen …

What Matters Most? A Scientific Advice Role Play on Estimands

Dr. Alexander Schacht

All Episodes

A replay of the PSI Conference 2018

Are you a sponsor who is seeking joint scientific advice from a regulatory agency and an HTA body?

If yes, this episode is for you. This presentation replicates the discussions which may go on during scientific advice. The example was in Respiratory. This roleplay was played by David Wright, Oliver Keene, Stephen Ruberg, and myself. Mouna Akacha moderated the discussion. The aim was to show a couple of discussion points and an interesting aspect that may come up with such discussions.

A lively debate followed about the differing needs of Regulatory agencies vs HTA, with the patient voice often not taking center stage.

Weiterlesen …