The Effective Statistician

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Picture shows: 2025 Lifestyle Planning

2025 Lifestyle Planning

In this episode, I explore these questions with Alun Bedding, a seasoned statistician who has recently ventured into the world of coaching. I’m thrilled to welcome Alun back to the show. He shares his inspiring journey from taking leadership courses to launching his own coaching business. We explore the value of having a coach, the transformative power of effective coaching practices, and practical advice for enhancing your professional skills.
Picture shows: Early Development and The Dose Selection in the Immune-oncology

Early Development and The Dose Selection in the Immune-oncology

How do we find the right dose in immune-oncology trials? Is the traditional “maximum tolerated dose” approach still enough, or should we also focus on efficacy? In this episode of The Effective Statistician, I talk with Teppo Huttunen, a seasoned statistician and Chief Executive Officer of EstiMates Oy. We uncover the shortcomings of the conventional … Weiterlesen …
Picture shows: Sharpen the saw

Sharpen The Saw

In this episode, I explore these questions with Alun Bedding, a seasoned statistician who has recently ventured into the world of coaching. I’m thrilled to welcome Alun back to the show. He shares his inspiring journey from taking leadership courses to launching his own coaching business. We explore the value of having a coach, the transformative power of effective coaching practices, and practical advice for enhancing your professional skills.
Picture shows: Why is it important to measure exposure to digital health interventions and how to tackle the challenge

Why is it important to measure exposure to digital health interventions and how to tackle the challenge

Welcome to this episode of The Effective Statistician! Today, I explore an exciting and rapidly growing field: digital health interventions. Have you ever wondered how to define engagement with these tools? Why does measuring engagement matter so much for their success? And how can statisticians solve the unique challenges that come with this digital space? … Weiterlesen …
Picture shows: Why Do Clinical Trials Impact The Climate Heavily And What We Can Do About It?

Why Do Clinical Trials Impact The Climate Heavily And What We Can Do About It?

Have you ever thought about how clinical trials affect the environment? I hadn’t, until I spoke with Annie Wright, a first-year PhD student at Imperial College who is passionate about greener research. In this episode, we uncover how clinical trials contribute to climate change, from travel emissions to operational inefficiencies. We dive into practical actions … Weiterlesen …
Picture shows: Introduction To Dealing With Non-Proportional Hazards

Introduction to Dealing with Non-proportional Hazards

Have you faced the challenge of dealing with non-proportional hazards in survival analysis? In this episode, I team up with Kaspar Rufibach, a statistical methodology expert, to break down what proportional hazards mean, why the assumption often fails, and how you can tackle these situations effectively. We explain key concepts like hazard functions, discuss practical … Weiterlesen …
Picture shows: How Real Leaders Help Their People Grow Professionally and As a Person

How Real Leaders Help Their People Grow Professionally and As a Person

Introduction to Episode: “How Real Leaders Help Their People Grow Professionally and Personally” What does it take to be a great leader? How do you build trust, inspire growth, and create real value for your team and organization? In this episode of The Effective Statistician, I sit down with Aziza Yormirzaeva and Klaus Breuer to … Weiterlesen …
Picture shows: Clinical Development of Gene Therapies

Clinical Development of Gene Therapies

What makes gene therapy so different from traditional drug development? How do we address safety when each patient only receives a single dose? And why are statisticians so essential in this process? In this episode of The Effective Statistician, I sit down with Oscar Segurado, an MD, PhD, an expert in gene and cell therapies, … Weiterlesen …
Picture shows: Statistical Topics in Gene Therapy

Statistical Topics in Gene Therapy

What if we could target genetic diseases at their root, offering lifelong cures instead of temporary solutions? And what role do statisticians play in making this breakthrough possible? In this episode of The Effective Statistician, I dive into the fascinating world of gene therapy—an area packed with both promise and complexity. I’m thrilled to finally … Weiterlesen …
Picture shows: Clinical Development Plans

Clinical Development Plans

What does it take to create an effective clinical development plan? How do our early decisions shape the path of a compound through clinical phases? And how can statisticians actively balance the demands of science, speed, and cost in drug development? In this special 400th episode of The Effective Statistician, I dive into these questions … Weiterlesen …