I once reviewed tables for a randomized study and noticed several comments about testing the baseline characteristics. The commenters were arguing which test would be best to test for the differences between the 2 randomized groups at baseline.
This made me first angry about the wasted time and then curious about the reasons, statisticians still do this.
In today’s episode, Benjamin and I discuss some backgrounds for baseline testing in randomized studies. We also recommend these further readings:
- Baseline comparisons and covariate fishing: Bad statistical habits we should have broken yesterday, by Stefan L. K. Gruijters
- Testing for baseline balance in clinical trials, by Stephen Senn
References:
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